Interpreter Signature on Sterilization Consent Form When telephone interpreter services are needed to complete the sterilization consent form for non-English speaking Medicaid recipients, the interpreter's signature, date of the interpreter's service and the language used are required on the sterilization consent form. In lieu of getting the interpreter's signature on the sterilization consent form at the time the service is provided, the interpreter who explains the procedure by telephone may fax or mail the attestation of their interpreter services. Criteria for the faxed or mailed attestation are as follows: The wording of the attestation should be taken directly from the sterilization consent form. The interpreter must write his or her signature and the date the interpreter services were rendered on the attestation form. The date of the recipient, interpreter and witness signatures must all be the same. The attestation form must include the recipient's name as it appears on the Medicaid ID card as well as the Medicaid ID number. A copy of the attestation must be attached to the consent form when the provider submits the statement to EDS, the fiscal agent. The provider must maintain the original attestation document with the consent form in the patient's medical record.
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Added to PDL: Starlix, Prandin Prior Authorization Criteria All agents in this class are available without PA. Estrogen Agents, Oral and Transdermal-Estrogens can be used for hormone replacement therapy, for the treatment of vasomotor symptoms, and the prevention of osteoporosis. Exogenous estrogens are metabolized in the same manner as endogenous estrogens. Transdermal delivery systems bypass the first pass metabolism in the liver. Therefore, the effects on the liver such as the changes in the lipid parameters are not seen with the transdermal systems. The dose delivered by the transdermal systems provides similar mean serum concentrations as the oral formulations with the same estrogenic effects. Added to PDL: Transdermal Estrogen Patches all brands and generics ; , Premarin, Menest, Estrace generic formulations of estradiol ; , Ortho-Est and Ogen all generic formulations of estropipate.
Comparative Efficacy Oral preparations - Conjugated equine estrogens Premarin ; , the most frequently prescribed estrogen product and therefore the most studied ; , are derived from the urine of pregnant mares. All other oral estrogens C.E.S., Estrace, Ogen ; are derived from plants. Regardless of source, all oral estrogens result in similar serum estrone and estradiol levels and there is no known advantage of one product over another when equivalent doses are used table 1 ; . For relief of menopausal symptoms, therapy can be initiated with low doses 0.3 mg of conjugated estrogen or equivalent ; and increased if symptoms are not relieved. Most vasomotor symptoms are relieved within a few days of starting estrogen. The minimum dose required to prevent cardiovascular disease or osteoporosis is uncertain. 0.625 mg daily of conjugated estrogen is the most frequently used dose. There is insufficient information to know if doses 0.625 mg daily are effective in preventing cardiovascular disease. One study suggests that 0.3 mg daily of esterified estrogen Estratab not available in Canada ; taken with 1g of elemental calcium prevents postmenopausal bone loss. The duration of therapy depends upon the indication. Short term therapy 5 years ; is usually indicated for relieving menopausal symptoms. The optimum duration of treatment has not been determined for the prevention of osteoporosis and cardiovascular disease, but a minimum of 10 years seems necessary to achieve a benefit. Lifelong therapy may be necessary, as cardiovascular protection is apparent only in current users of estrogen and bone density decreases when estrogen is stopped. Transdermal products - Transdermal estrogen Estraderm, Vivelle, Climara ; is as effective as oral estrogen in relieving menopausal symptoms and in increasing bone density. Transdermal estrogen has.
UNIVERSITY HOSPITAL OF LILLE, LILLE, FRANCE Several lines of evidence support the notion that cellular metabolism is disrupted in sepsis, not on the basis of inadequate tissue perfusion, but rather on the basis of impaired mitochondrial function. In other words, multiple organ failure in sepsis may occur on the basis of `cytopathic hypoxia'. If this hypothesis is correct, efforts to improve outcome in septic patients by monitoring and manipulation of cardiac output, systemic oxygen delivery DO2 ; and regional blood flow are doomed to failure. Instead, the focus should be on developing pharmacological strategies to restore normal mitochondrial function and cellular metabolism. This approach, however, is largely speculative. Whether there is a deficit in regional DO2, or whether dysoxia is related to the inability of the tissue cells to utilize available oxygen adequately, remains controversial. Tissue hypoxia A deficiency of tissues to extract oxygen is a prominent feature of the pathology of sepsis, the gut mucosa being specifically sensitive.1 This manifests itself as a condition where, despite apparent correction of global variables of DO2, signs of regional dysoxia, such as elevated lactate levels and enhanced gastrointestinal 4.
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Auditory vigilance and a more rapid and improved association of ideas 8, 11, 14, ; . Caffeine helps to repress the tendency toward "response blocking" that is generated by an extended performance of a monotonous task 1 ; . These improvements usually occur most significantly among individuals who have a temporary degree of degraded performance resulting from sleep-deprivation and or fatigue, and to a lesser extent, among individuals under "normal conditions" of plenty of rest 4, 5 ; . It has been noted that a "single dose" of caffeine of 150 to 250 mg equivalent to two cups of ground coffee or one Vivarin tablet ; can produce deterioration of performance on a psychomotor task that requires very delicate muscular coordination and very accurate timing 10, 15 ; . This is because caffeine will produce a slight tremor due to its excitatory effects on the nervous system.
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There is much more on safe and unsafe medications for rabbits but they are more on a symptom to symptom or ailment to ailment basis and prevacid.
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Clinical trials of medical treatments fda understanding clinical trials from the patient's perspective fda from test tube to patient: new drug development in the us fda is a trial for you.
Nother medication is suspected of having life-threatening side effects and may soon be pulled from the market. Avandia, the trade name for GlaxoSmithKline's diabetes drug rosiglitazone, was reported in the New England Journal of Medicine to increase heart attack risk by 43 percent. The analysis was conducted by Steven Nissen and Kathy Wolski of the Cleveland Clinic and compiled the results of 42 prior studies. In its defense, the manufacturer cited other studies that showed no increased risk. And no one has yet nailed down the mechanism by which Avandia would damage the heart, although possibilities include its tendency to boost low density lipoprotein "bad" ; cholesterol by an average of 19 percent ; , precipitate congestive heart failure, and reduce blood counts. For now, Avandia remains on the market. Avandia is the latest in a long series of drugs that have turned out to present serious potential risks. Just last December, Pfizer pulled the plug on torcetrapib, a drug that was supposed to raise high density lipoprotein "good" ; cholesterol, but was associated with unexpected deaths in human tests. Premarin, used for "hormone replacement, " increases the risk of heart disease, cancer, and stroke. The painkiller Vioxx caused thousands of deaths from heart attacks and strokes. All these cases have left public health officials and journalists wringing their hands, wondering what we can do if drugs let us down. The first answer, of course, is to focus on the causes of illness. No clinician believes that type 2 diabetes is caused by a rosiglitazone deficiency. Rather, it is largely the result of diet and lifestyle. Although genes play a role in susceptibility, the meaty, fatty Western diet is strongly associated with whether the disease manifests or not. Similarly, genes influence heart disease risk one way or another. A person who avoids tobacco and animal products and remains physically active has a strong measure of protection. Some doctors are pessimistic about the benefits of diet changes, because conventional diets have been disappointing. However, going a step further--eliminating avandia is the latest in a animal products, minimizing oils, and avoiding sugar and other high-glycemic-index foods--is dramatically more effective. Moreover, the "side effects" of vegetarian and long series of drugs that vegan diets are all good ones. In addition to helping control diabetes, they also trim have turned out to present waistlines, cut cholesterol, and lower blood pressure. serious potential risks. This does not mean that there is no role for medication. But most patients treated with medications have never had the benefit of a really good diet that might have prevented their condition or made it more manageable. So why are blockbuster drugs presenting unforeseen risks? Two reasons: First, drug companies now focus on products for long-term use. Rather than eking out profits from antibiotics used for a week or two or vaccines administered just once, they are investing in drugs designed to become a permanent part of your life. So toxicities that might not show up over the short run may well add up as the years go by. Second, drug companies continue to rely on animal tests, which often fail to show the dangers faced by human patients. Newer test methods that can more accurately predict the results in patients will mean safer medications. And when diet changes are used to their full effect, medications may be needed much less frequently and prilosec.
In early menopause when bone degradation and vasomotor symptoms are most pronounced. 4. The lowest effective doses of hormones for the individual patient should be used. 5. Alternative therapies that target specific organs tissues, such as hormone creams, selective estrogen receptor modulators and biophosphonates, should be considered. 6. Botanicals and their derivatives may have long-term effects that parallel or contradict results seen with CHRT. Thus, they should be used with caution. Despite these guidelines, patient choices on hormone replacement are daunting. With a long product history and staunch advocates, prempro persists in the market place. Hardly an outlaw drug, it will offer new formulations, at best with strident package labeling, in the near future. Since the opening of WHI enrollment, new data, new drugs and new formulations have been introduced. These drugs are all less well studied than premarin. Cautioned by WHI's multiple outcomes, physicians must create a matrix to facilitate educated choice. Amongst these factors are the patient's age, hysterectomy status, race, medical history, exercise levels and sexual activity. To be matched with these factors are numerous estrogen progestin formulations as well as more sublime selective estrogen receptor modulators.
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No apparent common motif in the chemical structure of these compounds, except that they all contain two phenyl groups. Molecular modeling further shows that the two benzene rings in all these drugs have very similar spatial orientations stem bond angle, 110 degrees; center center distance, 5 ; . In contrast, the two phenyl groups in phenylbutazone, a drug that has only a slight effect on Na current, are oriented in quite a different way. These findings strongly suggest that the two phenyl groups are the key ligands interacting with the channel. Because the binding counterpart of a benzene ring usually is also a benzene ring, some aromatic side chain groups of the Na channel presumably are realigned during the gating process to make the very different affinity to the aforementioned drugs between the inactivated and the resting channels.
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6.4.1 Female Sex Hormones 6.4.1.1 Oestrogens and HRT Oral Combination Products Prempak C A ; Premique Cycle Eleste Duet Femoston Oral Oestrogen Only Conjugated oestrogens Premarin ; Estradiol Elleste-Solo.
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Specialty drugs are medications that require special handling, administration, or monitoring. The M-CARE Specialty Drug List contains categories of medications that can only be dispensed through a specialty pharmacy. The contracted specialty pharmacies include OptionCare Specialty Pharmacy and Infusion Services as well as the University of Michigan Health System pharmacies. When using the OptionCare specialty pharmacy, providers must initially complete and fax the applicable enrollment form to OptionCare to start a specialty prescription. To access the current M-CARE Specialty Drug List and OptionCare enrollment forms, go to mcare Providers Pharmacy information Specialty Drug List and propoxyphene.
Of estrogen alone 46 ; . In agreement with these observations, our data show that DHEA, a compound with a predominantly androgenic influence, has apparently no deleterious effect on the serum lipid profile 43 ; . Similarly, no change in the concentrations of cholesterol, its subfractions, or triglycerides from those after treatment with estradiol alone has been observed after 6 months of therapy with estradiol plus testosterone implants 47 ; . It should be mentioned that a study in man has shown an inverse correlation between fetal serum DHEA-S and low density lipoproteins 48 ; . More recently, a correlation has been found between low serum testosterone and DHEA levels and increased visceral fat, a parameter of higher cardiovascular risk 16 ; . Administration of testosterone in moderate doses leading to plasma testosterone levels in the physiological range has even been found to induce a decrease in plasma triglyceride and cholesterol levels, a reduction in abdominal adipose cell LPL activity, as well as an increased lipolytic responsiveness of adipocytes to norepinephrine 49 51 ; . The percutaneous administration of testosterone in men with abdominal obesity led to decreased plasma triglycerides, cholesterol, and fasting blood glucose levels as well as decreased diastolic blood pressure. Such data indicate an improvement by androgens in the risk factors for cardiovascular disease 49 ; . Although the maximal 4.1% and 6.6% decreases in serum cholesterol observed at 6 months in our study did not reach the level of significance, possibly due to the small number of subjects 43 ; , such changes are comparable to the 2.8% decrease in serum cholesterol observed after 1 yr of replacement therapy with Premarin and Provera 52 ; . Such changes are also in agreement with the 3% decrease in total serum cholesterol achieved with percutaneous 17 -estradiol Estrogel ; and Utrogestan 28 ; and the 5.5% inhibition of the same parameter after treatment with Premarin and Utrogestan 28 ; . It should also be mentioned that the serum lipid levels in our cohort of subjects were within the normal range at the start of therapy, whereas it is recognized that the beneficial effects of replacement therapy with Premarin Provera depend upon the initial serum lipid values 53 ; . As HDL cholesterol appears to remain stable during the menopausal period, whereas LDL cholesterol increases 54 ; , our data showing a trend for decreased LDL levels 43 ; might represent another positive effect of DHEA treatment. Although androgens are gaining increased recognition for their specific beneficial effects in postmenopausal women, virilizing effects are observed with the use of testosterone 55, 56 ; . As examples of the beneficial effects of androgens, BMD measured in the lumbar spine, femoral trochanter, and total body was increased more by estrogen plus testosterone implants than by estradiol alone over a 24-month period 57 ; . Moreover, in established osteoporosis, anabolic steroids have been reported to help prevent bone loss 58 ; . Similarly, sc estradiol and testosterone implants have been found to be more efficient than oral estrogen in preventing osteoporosis in postmenopausal women 59 ; . Although the difference has been attributed to the different route of administration of estrogen, the cause of the difference could well be the action of testosterone. Androgen therapy, as observed with nandrolone decanoate, has been found to increase vertebral BMD in postmenopausal women 60 ; . The present data in.
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HS Number Description 930400 Other arms for example, spring, air or gas guns and pistols, truncheons ; , excluding those of heading 93.07. 9305 Parts and accessories of articles of headings 93.01 to 93.04. 930510 - Of revolvers or pistols - Of shotguns or rifles of heading 93.03 : 930521 -- Shotgun barrels 930529 -- Other - Other : 930591 -- Of military weapons of heading 93.01 930599 -- Other 9306 Bombs, grenades, torpedoes, mines, missiles and similar munitions of war and parts thereof; cartridges and other ammunition and projectiles and parts thereof, including shot and cartridge wads. 930610 - Cartridges for riveting or similar tools or for captive-bolt humane killers and parts thereof - Shotgun cartridges and parts thereof; air gun pellets : 930621 -- Cartridges 930629 -- Other - Other cartridges and parts thereof : 93063010 --- For military purposes --- Other : 93063091 ---- Cartrige parts 93063099 ---- Other - Other : 93069010 --- For military purposes 93069090 --- Other 930700 Swords, cutlasses, bayonets, lances and similar arms and parts thereof and scabbards and sheaths therefor. 9401 Seats other than those of heading 94.02 ; , whether or not convertible into beds, and parts thereof. 940110 - Seats of a kind used for aircraft 940120 - Seats of a kind used for motor vehicles 940130 - Swivel seats with variable height adjustment 940140 - Seats other than garden seats or camping equipment, convertible into beds 940150 - Seats of cane, osier, bamboo or similar materials - Other seats, with wooden frames : 940161 -- Upholstered 940169 -- Other - Other seats, with metal frames : 940171 -- Upholstered 940179 -- Other 940180 - Other seats 940190 - Parts 9402 Medical, surgical, dental or veterinary furniture for example, operating tables, examination tables, hospital beds with mechanical fittings, dentists' chairs barbers' chairs and similar chairs, having rotating as well as both reclining and elevating movements; parts of the foregoing articles. 940210 - Dentists', barbers' or similar chairs and parts thereof 940290 - Other 9403 Other furniture and parts thereof. 940310 - Metal furniture of a kind used in offices 940320 - Other metal furniture 940330 - Wooden furniture of a kind used in offices 940340 - Wooden furniture of a kind used in the kitchen 940350 - Wooden furniture of a kind used in the bedroom.
Four types of medical decision making are recognized: straightforward; low complexity; moderate complexity; and, high complexity. To qualify for a given type of decision making, two of the three elements in the table following must be met or exceeded: Number of diagnoses or management options minimal limited multiple extensive Amount and or complexity of data to be reviewed minimal or none limited moderate extensive Risk of complications and or morbidity or mortality minimal low moderate high Type of decision making and prozac and premarin.
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Efficacious than lower doses and demonstrated an Increase in extrapyramidal symptoms and other adverse effects. The satety of doses above 16 mg day has not been evaluated in clinical trialr tAntipsychotic activity is presumed to be mediated through a combination ot dopamine El2 and serotonin 5-HT2 antagonism, although the exact mechanism of action Is unknown. Please see brief summary of Prescribing Intormoflon the end of this advertisement. Janssen Pharmaceutica Inc. 1994 &echam at.
Diagnosis t increased levels of FSH 40 IU L ; decreased levels of estradiol Treatment t hormone replacement treatment doses much lower than OCP ; transdermal or oral cyclic estrogen Premarin ; 0.625 mg OD 1-25 plus progesterone Provera ; 10 mg OD, day 14 or 15, 16 ; to day 25, or long cycling Premarin 0.625 mg daily plus Provera 5 mg for 14 days q3 months, or continuous combined Premarin 0.625 mg plus Provera 2.5 mg daily unopposed estrogen increases the risk of endometrial cancer without the addition of Provera, but Provera is not needed if previous hysterectomy t calcium supplement t physical exercise t evening primrose oil Indications for Hormone Replacement Therapy t relief of symptoms - see above vasomotor, atrophy, insomnia ; t protection against osteoporosis t osteoporotic risk factors caucasian or oriental race thin habitus immobilization or physical inactivity estrogen deficiency premature menopause drugs: chronic corticosteroid therapy, chronic use of heparin, anticonvulsants, or thyroid replacement diet: low calcium, low vitamin D, high caffeine high alcohol, or high protein other factors: smoking, family history t cardiovascular protection estrogen significantly reduces risk of CAD decreases LDL and increases HDL Side Effects of HRT t abnormal uterine bleeding - requires endometrial biopsy if bleeding other than withdrawal bleeding with combined E P therapy t mastodynia t worse in progesterone phase of combined therapy t edema, weight gain, heartburn, nausea t controversy with respect to HRT and breast cancer risk Contraindications of HRT t absolute undiagnosed vaginal bleeding known or suspected cancer of breast or uterus acute liver disease or chronically impaired liver function acute vascular thrombosis or history of severe thrombophlebitis or thromboembolic disease t relative pre-existing uncontrolled hypertension uterine fibroids and endometriosis familial hyperlipidemias migraine headaches family history of estrogen-dependent cancer chronic thrombophlebitis diabetes mellitus gallbladder disease.
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2006 Avera Pharmaceuticals, Inc. averapharm text - Page 9.
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