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References: 1 Risks and benefits of estrogen plus progestin in healthy postmenopausal women. JAMA 2002; 288: 321-333. jama 2 Breast cancer and hormone replacement therapy in the Million Women Study. Lancet 2003; 362: 419. thelancet.
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Aposhian, H.V. et al 1990 ; meso-2, 3-Dimercaptosuccinic acid: Chemical, pharmacological and toxicological properties of an orally effective metal chelating agents. Annu. Rev. Pharmacol. Toxicol., 30, 279-306. Goyer, R.A. 1991 ; Toxic effects of metals, in Casarett and Doull's Toxicology: The Basic Science of Poisons, 4th edn, eds M.O. Amdur. et al ; , Pergamon Press, New York, pp. 623-680. Fernndez-Martn, J.L. et al 1994 ; Binding of aluminium to plasma proteins: Comparative effect of desferrioxamine and deferiprone L1 ; . Clin. Chim. Acta, 230, 137-145. Besunder, J.B. et al 1995 ; Short-term efficacy of oral dimercaptosuccinic acid in children with low to moderate lead intoxication. Paediatrics, 96, 683-687. Burns, C.B. et al 1995 ; The efficacy of chelation therapy and factors influencing mortality in lead intoxicated petrol sniffers. Aust. N. Z. J. Med., 25, 197-203. Kontoghiorghes, G.J. 1995 ; Comparative efficacy and toxicity of desferrioxamine, deferiprone and other iron and aluminium chelating drugs. Toxicol. Lett., 80, 1-18. Kontoghiorghes, G.J. 1995 ; New concepts of iron and aluminium chelation therapy with oral L1 deferiprone ; and other chelators. Analyst, 120, 845-851.
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Health and Human Services, and the Hospital Quality Alliance, made up of organizations representing consumers, healthcare professionals and government agencies. The intent: to help you make good health care decisions and to encourage hospitals to improve quality of care. After searching by hospital name or geography, you can see how often the facility provided the recommended care and compare its numbers to the average for all reporting hospitals in the same area and the nation. For pneumonia, quality measures include the percent of individuals given: a blood culture to see what kind of medicine would work best; a first dose of antibiotics within four hours of arrival at the hospital; the most appropriate initial antibiotic; and a pneumonia shot, which can help prevent the illness in the future. Why, for example, should you want to know if a person quickly received an antibiotic? "Early treatment with antibiotics can cure bacterial pneumonia and reduce the possibility of complications, " according to the Web site. After reviewing Hospital Care, keep digging. Check with your health care provider, State Survey Agency and the Quality Improvement Organization in your state. details hospitalcompare.hhs.gov or 877.696.6775.
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N AuGuST 23, 2005, 2-YEAR-OLD Mia LeBoeuf was admitted to Children's Hospital for cancer treatment. This was not her first time in the hospital. Mia was diagnosed with acute lymphocytic leukemia when she was just 17 months old. She was going through chemotherapy treatments, but her cancer relapsed. She had to go back in the hospital to prepare for a bone marrow transplant, but Mother Nature had another plan. Hurricane Katrina hit New Orleans August 29, six days after Mia re-entered the hospital. Like close to 100 other sick patients and their families, Mia and her parents, Carl and Loree, rode out the storm in the hospital. Katrina hit on a Monday morning. By Wednesday afternoon hospital administrators, unable to verify if the city could continue to supply enough water to run the hospital, were staging a full evacuation of all patients, families, physicians and staff. Children's Hospital made arrangements for Mia to go to Anderson Cancer Center in Houston. Carl and Loree drove west with Mia, a portable catheter still in her chest. They met Mia's two older sisters, Madeleine and Meredith, and her grandparents in southwest Louisiana, and the entire clan made it to Houston Friday morning. The family was safe, but Katrina did not spare their house. The Old Metairie neighborhood where the LeBoeufs lived did not flood, but a neighbor's tree fell on the house, causing severe damage. The house would need extensive repairs before anyone could live there again. The family settled in Houston for the next five months. Madeleine and Meredith attended school. Carl drove back and forth to New Orleans to work on the house. Loree spent most of her time at MD Anderson.
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1 Kokki H, Tuomilehto H. Pain management after adenoidectomy with ketoprofen: comparison of rectal and intravenous route. Br J Anaesth 1997; 85: 83640 Maunuksela E-L. Nonsteroidal anti-inammatory drugs in pediatric pain management. In: Schechter NL, Berde CB, Yaster M, eds. Pain in Infants, Children and Adolescents. Baltimore: Williams and Wilkins, 1993; 13543 3 Nikanne E, Kokki H, Tuovinen K. IV perioperative ketoprofen in small children during adenoidectomy. Br J Anaesth 1997; 78: 247 Nikanne E, Kokki H, Tuovinen K. Comparison of perioperative ketoprofen 2.0 mg kg1 with 0.5 mg kg1 i.v. in small children during adenoidectomy. Br J Anaesth 1997; 79: 6068 Kokki H, Nikanne E, Tuovinen K. I.v. intraoperative ketoprofen in small children during adenoidectomy: a dose-nding study. Br J Anaesth 1998; 81: 8704 Kokki H, Le Liboux A, Jekunen A, Montay G, Heikkinen M. Pharmacokinetics of ketoprofen syrup in small children. J Clin Pharmacol 2000; 40: 3549 Sepponen K, Kokki H, Ahonen R. Training of medical staff positively inuences postoperative pain management at home in children. Pharm World Sci 1999; 21: 16872 Sepponen K. Ahonen R, Kokki H. The effects of a hospital staff training program on the treatment practices of postoperative pain in children under 8 years. Pharm World Sci 1998; 20: 6672 Wolf AR. Tears at bedtime: a pitfall of extending paediatric day-case surgery without extending analgesia. Br J Anaesth 1999; 82: 31920 and tenormin.
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Improving Compliance Patients who decide to begin a drug regimen will need significant education about the particular drug's risks, benefits, side effects, method of administration, and dosage. Studies have shown that patients who maintain a good understanding of these issues will be more likely to comply with therapy and thereby achieve better outcomes. "While not all patients with hepatitis C need drug therapy, those who do must be compliant with their drug regimen in order to maximize the chances that the medication will improve their health, " Worman says. Coli agrees, saying, "Patient education increases compliance because it.