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Haney AF, Muscato JJ, Weinberg JB. Peritoneal fluid cell populations in infertility patients. Fertil Steril 1981; 35 6 ; : 696-8. Classic Kresch AJ, Seifer DB, Sachs LB, Barrese I. Laparoscopy in 100 women with chronic pelvic pain. Obstet Gynecol 1984; 64 5 ; : 672-4 Classic Barbieri RL, Niloff JM, Bast RC Jr, Scaetzl E, Kistner RW, Knapp RC. Elevated serum concentrations of CA-125 in patients with advanced endometriosis. Fertil Steril 1986; 45 5 ; : 630-4. Classic Kao LC, Germeyer A, Tulac S, Lobo S, Yang JP, Taylor RN, Osteen K, Lessey BA, Giudice LC. Expression profiling of endometrium from women with endometriosis reveals candidate genes for disease-based implantation failure and infertility. Endocrinology 2003; 144 7 ; : 2870-81 Important Buchweitz O. Staebler A. Tio J. Kiesel L. Detection of peritoneal endometriotic lesions by autofluorescence laparoscopy. J Obstet Gynecol 2006; 195 4 ; : 949-54 Important Lebovic DI; Mueller MD; Taylor RN. Immunobiology of endometriosis. Fertil Steril 2001; 75 1 ; : 1-10 Review Sagsveen M. Farmer JE. Prentice A. Breeze A. Gonadotrophin-releasing hormone analogues for endometriosis: bone mineral density. Cochrane Database of Systematic Reviews 2003; 4 ; : CD001297. Review Brosens I. Puttemans P. Campo R. Gordts S. Brosens J. Non-invasive methods of diagnosis of endometriosis. Curr Op Obstet Gynecol 2003; 15 6 ; : 519-22 Review Berkley KJ. Rapkin AJ. Papka RE. The pains of endometriosis. Science 2005; 308 5728 ; : 1587-9. Review Allen C. Hopewell S. Prentice A. Non-steroidal anti-inflammatory drugs for pain in women with endometriosis. Cochrane Database of Systematic Reviews 2005; 4 ; : CD004753. Review Hart RJ. Hickey M. Maouris P. Buckett W. Garry R. Excisional surgery versus ablative surgery for ovarian endometriomata. Cochrane Database of Systematic Reviews 2005; 3 ; : CD004992. Review Ferrero S. Abbamonte LH. Anserini P. Remorgida V. Ragni N. Future perspectives in the medical treatment of endometriosis. Obstetrical & Gynecological Survey 2005; 60 12 ; : 817-26. Review Somigliana E. Vigano' P. Parazzini F. Stoppelli S. Giambattista E. Vercellini P. Association between endometriosis and cancer: a comprehensive review and a critical analysis of clinical and epidemiological evidence. Gynecol Onc 2006; 101 2 ; : 331-41. Review. OR-062: Gruenwald et al. evaluates efficacy of SDTP on GPs' Rx readiness to ED. + ve. OR-036: Studies impact of various ED Rx modalities on QOL of Egyptian couples using validated instruments. Urges looking beyond penile rigidity. OR-028: Mulhall et al. Analyses predictors of outcomes with drug Rx of ED, post-RP. Rx + ve in majority. 4 predictors * identified. OR-035: Mulhall et al. Similar. 3 nation. Drug Rx , esp. among RP performers OR-039: Wang. Compares 2 & 3 piece IPPs using SHIM. Equally effective. OR-038: Salem et al. States that smaller IPPs can be used as tissue expanders over 8-12 m & upsized to larger IPPs later. OR-037: Delk et al. Long term, revision-free IPP survival. Prosp. study, 6000 opns, 14 models, 1 team, 20 yrs. 60 %, 15 + survival. OR-040: Wang et al. Simultaneous IPP-AUS after RP in 29 pts 5 yrs. PPs: pumps' & cuff placement and vioxx.

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A new class of potential drugs is based on removing ered either as proteins or as genes. the RNAs that code for the proteins that are causing damage. Promising preliminary results have been obtained for HuntMouse models of HD and ALS appear to have responded posiington's, Parkinson's, Alzheimer's, and prion diseases. For examtively to such treatments, which are delivered via gene therapies. ple, fruit flies Drosophila ; that get Huntington's disease HD ; Cell and gene therapy because they have been modified to carry the mutant human gene Researchers throughout the world are pursuing a variety of new are generally too weak and uncoordinated to break out of their ways to repair or replace neurons and other cells in the brain. pupal case the way normal insects do. However, when they also These experimental approaches are still being worked out in aniexpress the gene for an anti-HD antibody, all of them can emerge mals and cannot be considered therapies for humans at this time. as young adults. Furthermore, these treated flies live longer than Scientists have identified emthe untreated ones that do manbryonic neuronal stem cells -- age to emerge, and the treated Thousands of small molecule drug unspecialized cells that give rise ones show less pathology in to cells with specific functions-- their brains. candidates can be tested using high in the brain and spinal cord of Small molecules and embryonic and adult mice. Stem throughput screening to alter a cellular RNAs cells can continuously produce Clarifying the processes that all three major cell types of the property that represents an important underlie brain damage will open brain: neurons; astrocytes, the cells that nourish and protect up the potential to use small part of a disease process. neurons; and oligodendrocytes, molecule drugs to alter these the cells that surround axons and allow them to conduct their sigprocesses. Some success has occurred in developing animal modnals eciently. The production abilities of stem cells may someels using approaches based on known mechanisms of drugs. day be useful for replacing brain cells lost to disease. A more limExamples include drugs such as antibiotics and anti-tumor drugs, ited type of stem cell also has been discovered in the adult nervous which appear to reduce the neuronal damage in ALS, HD, and system in various kinds of tissue, raising the possibility that these Parkinson's disease. Thousands of small molecule drug candidates adult stem cells might be pharmacologically directed to replace can be tested using high throughput screening to alter a cellular damaged neurons. property that represents an important part of a disease process. In other work, researchers are studying a variety of viruses Because many neurodegenerative diseases involve proteins that that may ultimately be used to act as "Trojan horses, " carrying misfold and clump abnormally, lasers are used to measure therapeutic genes to the brain to correct nervous system diseases. whether proteins are clumped inside cells that have been robotiThe viruses include herpes simplex type 1 virus HSV ; , adenovirus, cally distributed into tiny wells, along with the small molecules to lentivirus, adeno-associated virus, and others naturally attracted be tested. A machine then scans the wells and reports whether parto neurons. It has been found that all can be modified to carry ticular drugs have changed the protein clumping, so that these new genes to cells in tissue culture and in the rodent central nerdrugs can be tested further. New leads for Alzheimer's and prion vous system. HSV and adenovirus vectors have also been evaludrugs have recently been described using these methods. ated in early-stage human trials for treating brain tumors. Several neurodegenerative diseases are caused by the accu and wellbutrin. Bill on paper. Must identify name, dosage & strength of drug in Remarks field. Reimbursement is based on average wholesale price + 10 percent. Taxol Oncaspar. Verify that used oil facilities have durable, legible signs that are readily visible. 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Elementary and high school youth to make healthy lifestyle choices. Columbus County Hospital, Wake Forest University School of Medicine, Public Schools of Robeson County, Whiteville Primary School and Hallsboro-Artesia Elementary School are joining the Medical Center to serve the target population. The project will follow 2 cohorts 1st and 9th graders ; over 3 years to assess changes during and after implementation of multi-faceted program that targets health at the student, family, organizational and community levels. In-school interventions include incorporating physical activity and nutrition into the daily curriculum. Community intervention includes nutrition and cooking education and improvements to the communities' options for living a healthy lifestyle. Lay Health Educators will assist in a train-the-trainer initiative to increase outreach into faith and family oriented communities.

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